Advancing Mitochondrial Science

The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.

What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.

This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Mitochondrial Testing Kit | Mitome
Cellular Health for Optimal Energy
Mitochondria Test

Featured Publications

Explore the research and insights advancing mitochondrial science and health.

  1. Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans

    Published By
    Horm Metab Res
    Published Date
    November 1, 2010
  2. Brief Communication: SIR-2.1-dependent lifespan extension of Caenorhabditis elegans by oxyresveratrol and resveratrol

    Published By
    SAGE Publications
    Published Date
    October 10, 2016
  3. a Gut Metabolite, Improves Insulin Sensitivity Through Augmentation of Mitochondrial Function and Biogenesis.

    Published By
    Obesity (Silver Spring)
    Published Date
    April 1, 2019
  4. Kaempferol ameliorates palmitate-induced lipid accumulation in HepG2 cells through activation of the Nrf2 signaling pathway.

    Published By
    Hum Exp Toxicol
    Published Date
    January 1, 2023
  5. Pancreas protective effects of Urolithin A on type 2 diabetic mice induced by high fat and streptozotocin via regulating autophagy and AKT/mTOR signaling pathway

    Published By
    Elsevier BV
    Published Date
    March 25, 2020
  6. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

    Published By
    Springer Science and Business Media LLC
    Published Date
    March 1, 2019
  7. Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI

    Published By
    American Physiological Society
    Published Date
    November 1, 2019
  8. Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis.

    Published By
    Redox Rep
    Published Date
    December 1, 2023
Chris Masterjohn, PhD, Founder & Chief Science Officer at Mitome, expert in mitochondrial function

Partner with Mitome™

Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.

Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.