Advancing Mitochondrial Science
The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.
What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.
This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Featured Publications
Explore the research and insights advancing mitochondrial science and health.
Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans
Published ByHorm Metab ResPublished DateNovember 1, 2010Brief Communication: SIR-2.1-dependent lifespan extension of Caenorhabditis elegans by oxyresveratrol and resveratrol
Published BySAGE PublicationsPublished DateOctober 10, 2016a Gut Metabolite, Improves Insulin Sensitivity Through Augmentation of Mitochondrial Function and Biogenesis.
Published ByObesity (Silver Spring)Published DateApril 1, 2019Kaempferol ameliorates palmitate-induced lipid accumulation in HepG2 cells through activation of the Nrf2 signaling pathway.
Published ByHum Exp ToxicolPublished DateJanuary 1, 2023Pancreas protective effects of Urolithin A on type 2 diabetic mice induced by high fat and streptozotocin via regulating autophagy and AKT/mTOR signaling pathway
Published ByElsevier BVPublished DateMarch 25, 2020Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
Published BySpringer Science and Business Media LLCPublished DateMarch 1, 2019Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI
Published ByAmerican Physiological SocietyPublished DateNovember 1, 2019Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis.
Published ByRedox RepPublished DateDecember 1, 2023

Partner with Mitome™
Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.
Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.