Advancing Mitochondrial Science

The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.

What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.

This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Mitochondrial Testing Kit | Mitome
Cellular Health for Optimal Energy
Mitochondria Test

Featured Publications

Explore the research and insights advancing mitochondrial science and health.

  1. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

    Published By
    Nature Publishing Group
    Published Date
    June 14, 2019
  2. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults

    Published By
    Elsevier
    Published Date
    May 17, 2022
  3. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial

    Published By
    American Medical Association
    Published Date
    January 4, 2022
  4. Partitioning of superoxide and hydrogen peroxide production by mitochondrial respiratory complex I

    Published By
    Biochim Biophys Acta
    Published Date
    March 1, 2017
  5. Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

    Published By
    Springer Science and Business Media LLC
    Published Date
    May 28, 2015
  6. Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition

    Published By
    Impact Journals, LLC
    Published Date
    October 4, 2021
  7. Epigallocatechin-3-gallate promotes healthy lifespan through mitohormesis during early-to-mid adulthood in Caenorhabditis elegans

    Published By
    Redox Biology
    Published Date
    September 29, 2017
  8. Resveratrol directly binds to mitochondrial complex I and increases oxidative stress in brain mitochondria of aged mice

    Published By
    Public Library of Science
    Published Date
    December 15, 2015
Chris Masterjohn, PhD, Founder & Chief Science Officer at Mitome, expert in mitochondrial function

Partner with Mitome™

Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.

Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.