Advancing Mitochondrial Science
The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.
What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.
This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Featured Publications
Explore the research and insights advancing mitochondrial science and health.
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Published ByNature Publishing GroupPublished DateJune 14, 2019Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
Published ByElsevierPublished DateMay 17, 2022Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial
Published ByAmerican Medical AssociationPublished DateJanuary 4, 2022Partitioning of superoxide and hydrogen peroxide production by mitochondrial respiratory complex I
Published ByBiochim Biophys ActaPublished DateMarch 1, 2017Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
Published BySpringer Science and Business Media LLCPublished DateMay 28, 2015Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition
Published ByImpact Journals, LLCPublished DateOctober 4, 2021Epigallocatechin-3-gallate promotes healthy lifespan through mitohormesis during early-to-mid adulthood in Caenorhabditis elegans
Published ByRedox BiologyPublished DateSeptember 29, 2017Resveratrol directly binds to mitochondrial complex I and increases oxidative stress in brain mitochondria of aged mice
Published ByPublic Library of SciencePublished DateDecember 15, 2015

Partner with Mitome™
Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.
Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.