"I don’t even know where to begin, but maybe “thank you” is a good start...
For several years, I had been experiencing on/off health problems that I didn’t initially think were serious issues—a constellation of seemingly disconnected problems. It started with digestive problems and eventually became more serious—including PVCs and tachycardia episodes that doctor’s initially believed were SVT episodes.
The latter didn’t happen very often, but would under certain conditions. Having extra sodium in my diet seemed to help somewhat, but I knew something wasn’t normal. I just didn’t know what.
I was also having trouble recovering from my training (weightlifting) and even just long walks with the dog. I would take excessively long naps (3-4hrs) during the day because I was so exhausted, I couldn’t keep my eyes open, and (oddly enough) had trouble sleeping through the night. I never felt truly rested. Over time, I started developing infrequent PVCs, which went from being infrequent to frequent.
It all came to a head last April (2025) when I was rushed to the ER after a tachycardia episode during a routine morning walk where I experienced a sustained heart rate of 190 bpm for 20-25 minutes. Heart was fluttering and by the time I got to the ER, I was barely able to stand. As soon as they administered saline, I converted instantly to normal sinus rhythm.
After that event, echocardiogram performed at my cardiologist’s office and MyZio (heart monitor worn for 2 weeks) confirmed PACs and frequent VE/PVCs at 72,289 isolated events over a period of 2 weeks. No other structural problems, aFib or any other problems, but it was distressing enough.
I was scared out of my mind, thought I was surely going to die, and no doctor could offer me any advice except medication to control them or potentially ablation surgery if the SVT came back. They assured me everything was going to be OK and it wasn’t life-threatening, but I knew this wasn’t normal for me. I’ve never been this way, and I spent considerable time and energy trying to stay active and eat healthy. But, in spite of my efforts, there were issues I seemed unable to control, like an expanding waistline, frequent aches and pains, and random, seemingly unexplainable and disconnected, nagging issues that didn’t seem to have any obvious solution and which no doctor had any meaningful or helpful insight or opinion about.
In the fall, I discovered your Mitome service and gave it a shot. I wasn’t getting any real answers elsewhere, and the digestive distress and PVCs were driving me insane. You had mentioned digestive upset potentially being linked to mitochondrial health. At that point, I had little to lose and everything to gain. I was told to just live with the PVCs, so I wrote them off as “this is just how it is now”.
Mitome results showed my complex II+III was functioning at 11%. Initial morning fasting lactate levels were 3.4 mmol/L. I can only guess what they spiked to during the day or strenuous (or even mild) physical activity. I followed the steps in my report and eventually my lactate levels came way down—not immediately but eventually it did come down. To my surprise I discovered multiple nutritional deficiencies as well, in spite of eating a nutrient-dense diet.
The protocol seemed to have a positive effect within 3-4 days, dropping my lactate levels in the mid 2s. Higher supplementation caused further drops until I hit 1.5. Correcting/working on correcting those nutritional deficiencies seems to have further improved this, dropping lactate below 1 mmol/L.
But… one of the more interesting things (to me, anyway) is once my lactate levels dropped below 2mmol/L, the PVCs stopped completely. I also haven’t had another tachycardia episode. I don’t feel the same sense of dread as I did before. I’m not fearful or scared to push myself to my limits. Lactate levels now are stabilized below 1, with occasional spikes up to 1.2 or 1.5.
Digestion is completely normalized—I feel like I can eat anything, including high FODMAP foods, without any digestive distress. I don’t need digestive bitters or enzymes at all, whereas before… I relied on both for even small meals, and still faced some digestive upset afterwards. And without the enzymes and bitters, it was even worse.
It also used to be that I was unable to eat eggs (or could only eat them very very sparingly) due to extremely painful digestive upset afterwards. Now I can eat as many eggs as I want, which is great because I love eggs and have at least 2 of them every day.
I sleep like a rock now, and feel recovered every morning, even on the occasional days when I don’t get a full 8 hours. Before, I slept (very poorly) for 10 hours at night and woke up tired. Now I sleep 7-8 hours and wake up feeling amazing.
I’m recovering from workouts and back to making progress in the gym. I’ve lost about 10lbs (give or take), my waistline has decreased from 40” to 35” (and counting), and yet… the weight on the bar keeps increasing and I keep getting stronger. I’ve even set some new all-time PRs in the gym on some difficult (for me) lifts.
I’m not the type of person to believe in miracles, but I can’t think of a better word to describe it—it’s “miraculous”. I feel like a new man. I’m sure there some more things I can improve, but even now… I have an entirely new perspective on, and renewed enthusiasm for, life. Before, it seemed hopeless. Now, I feel like I can do anything.
You’ve given me my life back. That is a debt I cannot repay. Thank you again for everything you’re doing with Mitome, and the continuing education around mitochondrial health.
If you have ever wondered whether you are really making a difference in anyone’s life, don’t. You are. Please keep up the great work.
Thank you, again."
"I went into unexplained menopause at 28 years old for ten years, and nothing could restore my ability to menstruate without medication or hormone treatment. I tried everything, unsuccessfully— conventional medicine, functional medicine, homeopathy, alternative therapies, diet and fitness changes, you name it.Just two weeks after trying one supplement Chris identified from my cheek swab as critical for my mitochondrial health, I began menstruating again. 100% true story."
"Very in-depth info on much of what is important for health… Here one gets insights that one cannot find in other places and that is approached from different angles."
"I have been struggling with severe episodes of reflux, extreme fatigue and stomach issues that have been getting worse and worse in the past few years. I was really starting to lose hope until I stumbled upon Dr Chris Masterjohn's work. I found out from the analysis that I had mitochondrial dysfunction affecting my cellular energy production, but it was something that could be fixed with targeted supplementation. The mitochondrial support I received has changed my life. I now can eat food and actually feel energized afterwards as my cells are properly converting nutrients into energy, it has made life so much more rewarding and fulfilling and I cannot thank Chris enough!"
"For a year after chemotherapy, I struggled with deep fatigue, brain fog, and scars that did not heal completely. This was the first time I found someone who looked at my issues as a mitochondrial dysfunction problem. Dr. Masterjohn suggested what I could do to test certain mitochondrial pathways that might be impaired based on the Mitome test results. These included diet changes to support cellular energy production, specific supplements targeting mitochondrial function, and therapy to boost mitochondrial activity. The resulting surge in cellular energy allowed me to start a strength training program, replacing muscle lost to muscle atrophy from chemotherapy. Scarring from treatment that was static for over a year completed healing and autoimmune issues settled down. This improvement in mitochondrial function was a significant turning point in my recovery and I'm looking forward to continued progress."
"The Mitome report’s supplement adjustments have been a game-changer. I used to struggle with frequent colds, a racing heart after caffeine or carbs, and low stress tolerance, which impacted my well-being and focus. Now, my energy is up, my blood sugar is steady, and I feel healthier and more productive overall. I’ve also fallen in love with music again, and my mood has greatly improved."
"I (34M) was a previously healthy 32 year old before I started having a myriad of health issues relating to stopping long term SSRI use. My symptoms were severe and included tachycardia, shortness of breath, neuropathy, sexual dysfunction, anxiety, muscle cramping, numbness, excessive urination. The constellation of symptoms brought me to see dozens of specialists who could not tell me what was going on. I am so grateful I came across Chris' work. Through the analysis, we discovered significant impairments in my mitochondrial electron transport chain, particularly in Complex II and III.
After reviewing my genetic data and mitochondrial function tests, we identified several key areas where my cellular energy production was compromised. Through targeted support of my mitochondrial pathways based on these findings, I quickly began to recover. This is after almost 2 years of being constantly sick. 6 months later, I have regained quality of life and am able to do everything I used to be able to. I am so thankful for Chris and his ability to discern how mitochondrial dysfunction can undermine many medical conditions. When I received the final report, he provided a clear protocol on how to improve my cellular energy production. I continue to improve weekly and am so excited for the future."
“It took about six months before I began to notice a major shift—but when it happened, it was profound. Almost overnight, I experienced a complete cessation of the negative emotional states I had lived with for so long—depression, anxiety, and mental fatigue simply stopped. Since that moment, any experience of mental or physical discomfort feels more like an observation than a struggle. This shift has made it much easier for me to relax and stay centered—something that used to be incredibly difficult. Recently, I decided to do a second round of mito.me testing, just over a year after starting the treatment, to see how far my mitochondrial function has come. I'm incredibly glad I repeated the test. I’m deeply grateful to Chris and the entire team who supported me through this journey. Their help has been instrumental in restoring my vitality—and for that, I truly thank them.”
“Great test. Results look great. Comprehensive suggestions to correct any issues are provided.”
“Mitome is my #1 lab testing recommendation and finally a lab testing that makes sense, as it goes straight to the root.”
"This test can be enormously insightful especially used in conjunction with LLM and other data points (lab results, genetic testing, etc.)! Actionable insights are broad, but the information itself is extremely detailed and helpful for identifying potential bottlenecks in energy optimization!"
"You have to start here, otherwise you're spinning your wheels and all your hard earned efforts may be hurting you instead of helping you."
"It might be the most valuable health insights they have ever received and they wont get the level of detail provided here anywhere else."
"The Mitome test is a one-of-a-kind evaluation of your mitochondrial function, with concrete recommendations for which nutrients to seek and which to avoid."
"If you've struggled for a long time with multiple health issues, esp involving multiple systems, consider doing the Mitome test. It may give you important insights as to major root causes. It lays out steps to take and how to take them. Be prepared to follow a comprehensive plan of action (which can be challenging, demanding, and costly). You may be asked to buy a lactate meter, which isn't cheap -- I tried to find a way around this, but came to understand its importance and that no, there wasn't a way around it if I want to properly figure things out."
