Mitome Kit
- Access the first comprehensive mitochondrial pattern analysis
- Leverage advanced proprietary technology
- Discover exactly what your cells need to thrive
- Transform your energy, performance, and longevity
Your Complete Analysis Includes
Our mission is to be the driving force behind mitochondrial wellness, revolutionizing the way we understand and optimize human health from the cellular level. Through advanced pattern analysis, we uncover your specific cellular needs and create precise protocols to maximize your mitochondrial efficiency.
- Mitochondrial Health Assessment
- Custom Food Recommendations
- Supplement Recommendations
- Personalized Protocol
- Mitome™ Analysis Kit
35,523*
*Clinical Studies analyzed to create precise protocols
50%
of All Cellular Damage Contributes to Mitochondrial Dysfunction
1,500
Optimization Pathways Identified through research
Real Stories, Real Results
Personal stories from those who unlocked their mitochondrial insight—and changed how they live.
"I don’t even know where to begin, but maybe “thank you” is a good start...
For several years, I had been experiencing on/off health problems that I didn’t initially think were serious issues—a constellation of seemingly disconnected problems. It started with digestive problems and eventually became more serious—including PVCs and tachycardia episodes that doctor’s initially believed were SVT episodes.
The latter didn’t happen very often, but would under certain conditions. Having extra sodium in my diet seemed to help somewhat, but I knew something wasn’t normal. I just didn’t know what.
I was also having trouble recovering from my training (weightlifting) and even just long walks with the dog. I would take excessively long naps (3-4hrs) during the day because I was so exhausted, I couldn’t keep my eyes open, and (oddly enough) had trouble sleeping through the night. I never felt truly rested. Over time, I started developing infrequent PVCs, which went from being infrequent to frequent.
It all came to a head last April (2025) when I was rushed to the ER after a tachycardia episode during a routine morning walk where I experienced a sustained heart rate of 190 bpm for 20-25 minutes. Heart was fluttering and by the time I got to the ER, I was barely able to stand. As soon as they administered saline, I converted instantly to normal sinus rhythm.
After that event, echocardiogram performed at my cardiologist’s office and MyZio (heart monitor worn for 2 weeks) confirmed PACs and frequent VE/PVCs at 72,289 isolated events over a period of 2 weeks. No other structural problems, aFib or any other problems, but it was distressing enough.
I was scared out of my mind, thought I was surely going to die, and no doctor could offer me any advice except medication to control them or potentially ablation surgery if the SVT came back. They assured me everything was going to be OK and it wasn’t life-threatening, but I knew this wasn’t normal for me. I’ve never been this way, and I spent considerable time and energy trying to stay active and eat healthy. But, in spite of my efforts, there were issues I seemed unable to control, like an expanding waistline, frequent aches and pains, and random, seemingly unexplainable and disconnected, nagging issues that didn’t seem to have any obvious solution and which no doctor had any meaningful or helpful insight or opinion about.
In the fall, I discovered your Mitome service and gave it a shot. I wasn’t getting any real answers elsewhere, and the digestive distress and PVCs were driving me insane. You had mentioned digestive upset potentially being linked to mitochondrial health. At that point, I had little to lose and everything to gain. I was told to just live with the PVCs, so I wrote them off as “this is just how it is now”.
Mitome results showed my complex II+III was functioning at 11%. Initial morning fasting lactate levels were 3.4 mmol/L. I can only guess what they spiked to during the day or strenuous (or even mild) physical activity. I followed the steps in my report and eventually my lactate levels came way down—not immediately but eventually it did come down. To my surprise I discovered multiple nutritional deficiencies as well, in spite of eating a nutrient-dense diet.
The protocol seemed to have a positive effect within 3-4 days, dropping my lactate levels in the mid 2s. Higher supplementation caused further drops until I hit 1.5. Correcting/working on correcting those nutritional deficiencies seems to have further improved this, dropping lactate below 1 mmol/L.
But… one of the more interesting things (to me, anyway) is once my lactate levels dropped below 2mmol/L, the PVCs stopped completely. I also haven’t had another tachycardia episode. I don’t feel the same sense of dread as I did before. I’m not fearful or scared to push myself to my limits. Lactate levels now are stabilized below 1, with occasional spikes up to 1.2 or 1.5.
Digestion is completely normalized—I feel like I can eat anything, including high FODMAP foods, without any digestive distress. I don’t need digestive bitters or enzymes at all, whereas before… I relied on both for even small meals, and still faced some digestive upset afterwards. And without the enzymes and bitters, it was even worse.
It also used to be that I was unable to eat eggs (or could only eat them very very sparingly) due to extremely painful digestive upset afterwards. Now I can eat as many eggs as I want, which is great because I love eggs and have at least 2 of them every day.
I sleep like a rock now, and feel recovered every morning, even on the occasional days when I don’t get a full 8 hours. Before, I slept (very poorly) for 10 hours at night and woke up tired. Now I sleep 7-8 hours and wake up feeling amazing.
I’m recovering from workouts and back to making progress in the gym. I’ve lost about 10lbs (give or take), my waistline has decreased from 40” to 35” (and counting), and yet… the weight on the bar keeps increasing and I keep getting stronger. I’ve even set some new all-time PRs in the gym on some difficult (for me) lifts.
I’m not the type of person to believe in miracles, but I can’t think of a better word to describe it—it’s “miraculous”. I feel like a new man. I’m sure there some more things I can improve, but even now… I have an entirely new perspective on, and renewed enthusiasm for, life. Before, it seemed hopeless. Now, I feel like I can do anything.
You’ve given me my life back. That is a debt I cannot repay. Thank you again for everything you’re doing with Mitome, and the continuing education around mitochondrial health.
If you have ever wondered whether you are really making a difference in anyone’s life, don’t. You are. Please keep up the great work.
Thank you, again."
David Lewis
"I went into unexplained menopause at 28 years old for ten years, and nothing could restore my ability to menstruate without medication or hormone treatment. I tried everything, unsuccessfully— conventional medicine, functional medicine, homeopathy, alternative therapies, diet and fitness changes, you name it.Just two weeks after trying one supplement Chris identified from my cheek swab as critical for my mitochondrial health, I began menstruating again. 100% true story."
Jacqueline R.
"Very in-depth info on much of what is important for health… Here one gets insights that one cannot find in other places and that is approached from different angles."
Alphonse Van C.
"I have been struggling with severe episodes of reflux, extreme fatigue and stomach issues that have been getting worse and worse in the past few years. I was really starting to lose hope until I stumbled upon Dr Chris Masterjohn's work. I found out from the analysis that I had mitochondrial dysfunction affecting my cellular energy production, but it was something that could be fixed with targeted supplementation. The mitochondrial support I received has changed my life. I now can eat food and actually feel energized afterwards as my cells are properly converting nutrients into energy, it has made life so much more rewarding and fulfilling and I cannot thank Chris enough!"
Michael Connolly
"For a year after chemotherapy, I struggled with deep fatigue, brain fog, and scars that did not heal completely. This was the first time I found someone who looked at my issues as a mitochondrial dysfunction problem. Dr. Masterjohn suggested what I could do to test certain mitochondrial pathways that might be impaired based on the Mitome test results. These included diet changes to support cellular energy production, specific supplements targeting mitochondrial function, and therapy to boost mitochondrial activity. The resulting surge in cellular energy allowed me to start a strength training program, replacing muscle lost to muscle atrophy from chemotherapy. Scarring from treatment that was static for over a year completed healing and autoimmune issues settled down. This improvement in mitochondrial function was a significant turning point in my recovery and I'm looking forward to continued progress."
Anita S.
"The Mitome report’s supplement adjustments have been a game-changer. I used to struggle with frequent colds, a racing heart after caffeine or carbs, and low stress tolerance, which impacted my well-being and focus. Now, my energy is up, my blood sugar is steady, and I feel healthier and more productive overall. I’ve also fallen in love with music again, and my mood has greatly improved."
Nav S.
"I (34M) was a previously healthy 32 year old before I started having a myriad of health issues relating to stopping long term SSRI use. My symptoms were severe and included tachycardia, shortness of breath, neuropathy, sexual dysfunction, anxiety, muscle cramping, numbness, excessive urination. The constellation of symptoms brought me to see dozens of specialists who could not tell me what was going on. I am so grateful I came across Chris' work. Through the analysis, we discovered significant impairments in my mitochondrial electron transport chain, particularly in Complex II and III.
After reviewing my genetic data and mitochondrial function tests, we identified several key areas where my cellular energy production was compromised. Through targeted support of my mitochondrial pathways based on these findings, I quickly began to recover. This is after almost 2 years of being constantly sick. 6 months later, I have regained quality of life and am able to do everything I used to be able to. I am so thankful for Chris and his ability to discern how mitochondrial dysfunction can undermine many medical conditions. When I received the final report, he provided a clear protocol on how to improve my cellular energy production. I continue to improve weekly and am so excited for the future."
Miguel G
“It took about six months before I began to notice a major shift—but when it happened, it was profound. Almost overnight, I experienced a complete cessation of the negative emotional states I had lived with for so long—depression, anxiety, and mental fatigue simply stopped. Since that moment, any experience of mental or physical discomfort feels more like an observation than a struggle. This shift has made it much easier for me to relax and stay centered—something that used to be incredibly difficult. Recently, I decided to do a second round of Mitome testing, just over a year after starting the treatment, to see how far my mitochondrial function has come. I'm incredibly glad I repeated the test. I’m deeply grateful to Chris and the entire team who supported me through this journey. Their help has been instrumental in restoring my vitality—and for that, I truly thank them.”
Matt B.
“Great test. Results look great. Comprehensive suggestions to correct any issues are provided.”
Taylor T
“Mitome is my #1 lab testing recommendation and finally a lab testing that makes sense, as it goes straight to the root.”
Silke De Oca
"This test can be enormously insightful especially used in conjunction with LLM and other data points (lab results, genetic testing, etc.)! Actionable insights are broad, but the information itself is extremely detailed and helpful for identifying potential bottlenecks in energy optimization!"
Melissa B.
"You have to start here, otherwise you're spinning your wheels and all your hard earned efforts may be hurting you instead of helping you."
Tracy C.
"It might be the most valuable health insights they have ever received and they wont get the level of detail provided here anywhere else."
Steven K.
"The Mitome test is a one-of-a-kind evaluation of your mitochondrial function, with concrete recommendations for which nutrients to seek and which to avoid."
Paul P.
"If you've struggled for a long time with multiple health issues, esp involving multiple systems, consider doing the Mitome test. It may give you important insights as to major root causes. It lays out steps to take and how to take them. Be prepared to follow a comprehensive plan of action (which can be challenging, demanding, and costly). You may be asked to buy a lactate meter, which isn't cheap -- I tried to find a way around this, but came to understand its importance and that no, there wasn't a way around it if I want to properly figure things out."
Arnold J.
Why Personalized Mitochondrial Analysis Matters
Our breakthrough technology
- Measures the activity of all the major complexes in the electron transport chain
- Identifies your unique pattern among 12 distinct types
- Measure your actual mitochondrial function
- Create precise optimization protocols
- Deliver targeted recommendations for your pattern type
90% of Your Cellular Energy is Produced by Mitochondria.
We’re the first to analyze how well yours actually work.
1,500 Mitochondrial Enhancement Pathways
Your mitochondria influence every aspect of your health – from cellular energy production to cognitive function, from physical performance to longevity. Through advanced analysis of your unique mitochondrial pattern, we’ve found that there are over 1,500 distinct ways to optimize your cellular function. This unprecedented level of precision allows us to enhance your body's performance at its very foundation.
Our advanced technology measures the activity of all the major complexes in the electron transport chain, identifying your unique pattern among 12 distinct types. This precise analysis allows us to map optimization opportunities across critical biological systems:
- Physical performance and recovery
- Cellular repair and longevity
- Energy production and metabolism
- Brain function and cognitive performance
- Immune system strength
- Sleep quality and restoration
- Stress adaptation and resilience
Our Focus
This breakthrough analysis reveals targeted interventions that enhance your cellular efficiency at its source, optimizing your body’s fundamental processes through precise measurement of respiratory chain complexes.
- Performance & Longevity
- Energy & Cellular Optimization
- Cognitive Function & Mental Health
- Aging & Cellular Repair
Scientific Innovation
Our patent-pending technology is backed by extensive scientific research and clinical studies.
Frequently Asked Questions
Read More FAQsWhat is Mitome and how does it work?
Mitome is the first mitochondrial health analysis that identifies functional impairments in your cellular energy production system, where 90% of your energy is made. Using a non-invasive cheek swab, we assess four key biomarkers of mitochondrial respiratory chain activity. This scientific insight allows us to recommend a personalized optimization protocol based on your specific mitochondrial type.
Without understanding your unique mitochondrial pattern, you may waste time and money on ineffective supplements. Mitome helps you target the specific issues affecting your mitochondrial function, ensuring your optimization efforts are focused on what will actually work for you.
What is the science behind this test?
Mitome uses a proprietary, multi-layered analysis to assess mitochondrial function in a way no blood test, genetic screen, or hormone panel can.
We measure five critical components of your mitochondrial respiratory chain—key drivers of how your cells produce energy at the molecular level. By analyzing these components together, we identify your unique mitochondrial pattern, which reflects the specific inefficiencies or bottlenecks in your cellular energy system.
Imagine your cellular energy system as a road with four critical stop signs—each one representing a checkpoint in your mitochondrial pathway. If traffic flows smoothly, energy production runs efficiently. But if there’s a slowdown, a stop sign is blocked, or a detour forces energy down a less efficient route, your whole system can lag—leading to fatigue, poor recovery, and other performance issues.
Mitome identifies exactly where these slowdowns or detours are happening in your mitochondrial “roadmap,” so we can guide you with targeted recommendations to clear the path and restore optimal energy flow.
For more technical details, see the "How We Measure" section on our Science and Testing page.
Who should take this test?
Mitome is ideal for three groups:
- People with chronic, unresolved health issues
- Individuals focused on optimizing performance and longevity
- Anyone interested in understanding their unique mitochondrial function
What benefits will I see from taking the Mitome test?
The beauty of mitochondrial optimization is that improvements show up in the health areas that matter most to you. Since cellular energy fuels every bodily process, enhancing mitochondrial function creates a ripple effect of positive changes.
Track the metrics that align with your personal health goals:
- Energy seekers often see sustained energy throughout the day, reduced afternoon crashes, and feeling refreshed upon waking
- Fitness enthusiasts typically notice improved workout performance, faster recovery times, and better endurance
- Cognitive performance focused individuals frequently experience sharper mental clarity, better focus, and enhanced memory
- Sleep quality improvers commonly report deeper, more restorative sleep and easier mornings
- Metabolic health trackers often see more stable blood sugar, improved body composition, and better appetite regulation
- Stress management focused people usually notice greater resilience to daily stressors and improved mood stability
Your personalized mitochondrial optimization plan will support whatever health goals are most important to you, because better cellular energy production enhances your body's ability to excel in every area.
How does mitochondrial dysfunction show up?
Mitochondria are the powerhouses of the cell where nearly all cellular energy is produced. Energy metabolism fuels every single process in the body, including healthy sleep, alertness, supporting libido, hormonal balance, exercise performance, and cognitive performance, optimizing blood glucose, and protecting against heart disease and cancer. All health problems are influenced by cellular energy production.
Since mitochondria are your cells' powerhouses, producing nearly all the energy your body needs, poor mitochondrial function affects virtually every aspect of your health.
Common signs of mitochondrial dysfunction include:
- Persistent fatigue and low energy that doesn't improve with rest
- Poor sleep quality and difficulty waking up refreshed
- Brain fog, memory issues, and reduced mental clarity
- Decreased exercise performance and slower recovery
- Hormonal imbalances affecting mood, metabolism, and libido
- Blood sugar instability and difficulty maintaining healthy glucose levels
- Reduced stress resilience and slower healing
Long-term health implications:
Compromised mitochondrial function increases your risk of serious conditions including heart disease, diabetes, and cancer. This is because every cellular process, from immune function to tissue repair, depends on adequate energy production.
The reality is that all health problems are influenced by cellular energy production. When your mitochondria aren't functioning optimally, your entire body operates below its potential. That's why addressing mitochondrial health often leads to improvements across multiple areas of wellness, not just increased energy levels.
Optimizing your mitochondrial function is essentially upgrading your body's fundamental operating system.
Can I show my functional doctor this test?
Absolutely. Your personalized report includes a detailed explanation of the underlying science, the potential health implications of your mitochondrial pattern, and the rationale behind each recommendation. You're encouraged to share the protocol with your functional or integrative doctor to get their input and support.
When will I see those benefits?
The average lifespan your mitochondria is close to 3 months. While you may see immediate results if you add a supplement that resolves a major bottleneck, you should expect many of your benefits to become clear over the course of three months. Often fixing mitochondrial function changes vicious cycles into virtuous cycles: this can mean your benefits continue to accrue and mature for years to come.
Why is this new and different?
Many programs look at your genetics, your blood biochemistry, your saliva hormones, or your stool microbiome. But we are the first test to characterize the function of your mitochondria, where 90% of your cellular energy is made.
Without understanding your unique mitochondrial pattern, you may waste time and money on ineffective supplements. This test helps you target the specific issues affecting your mitochondrial function, ensuring your optimization efforts are focused on what will actually work for you.
Will you give me supplement recommendations?
Yes, we give recommendations based on your unique mitochondrial pattern. The recommendations are designed for long-term implementation. As you follow the protocol, you'll be able to evaluate which supplements are most effective for you and adjust accordingly based on your results.
Will medications or supplements interact with my results?
The test measures your current mitochondrial function, including any effects from medications or supplements you're taking. For the most accurate picture of your day-to-day mitochondrial health, we recommend maintaining your regular regimen when taking the test. If you're interested in understanding your baseline mitochondrial function without medications or supplements, you would need to discontinue them for 3 months before testing – however, this should only be done under the guidance of your healthcare practitioner.
So, you are going to know the state of your mitochondria while taking those supplements, but Chris lays out what supplements specifically are good and bad for your unique mitochondrial pattern. The recommendations are designed for long-term implementation. As you follow the protocol, you'll be able to evaluate which supplements are most effective for you and adjust accordingly based on your results.
Is this a DNA test?
No, this is not a DNA test. It’s is a non-invasive test that quantitatively and qualitatively analyzes the Electron Transport Chain (ETC) of the mitochondria to evaluate mitochondrial dysfunction. Your data will be generated by our lab partner and distributed through us.
Mitome goes very in-depth on the implications of how the mitochondrial respiratory chain is functioning and we deliver a 11-30 page report based on that. Without understanding your unique mitochondrial pattern, you may waste time and money on ineffective supplements. Mitome helps you target the specific issues affecting your mitochondrial function, ensuring your optimization efforts are focused on what will actually work for you.
Can the Mitome test detect whether the dysfunction is due to a gene mutation?
Genetics loads the gun, and environment pulls the trigger. Genetics tells you what could happen, and it can explain what you know is happening, but it never tells you what is happening. Mitome tells you what *is* happening in your mitochondria and what can be done about it. The protocols address it from a perspective that it reflects some mix of your genetics and your environment, and then gives you a protocol that includes things to help optimize your mitochondria based on both genetic and environmental causes of the patterns found.
Welcome to the Mitochondrial Revolution.
We’re done playing small. While others sell surface-level hacks, we go to the source—your mitochondria. Join the first real movement in health.
