Decoding the Science of Cellular Energy

We translate complex mitochondrial science into clear, actionable insights that transform human health and longevity. No more guessing - discover exactly what your mitochondria need to thrive.

Testing Guide: Unlock Your Cellular Potential

Four steps to optimize your mitochondrial health.

The Process is Simple

1

Order Your Test

Your comprehensive kit arrives at your door, complete with everything you need.

2

Complete Your Form.

Fill out the requisition form by providing your name, date of birth, and signature.

3

Quick Sample Collection

A simple 5-minute buccal cheek swab you can do at home. No blood draws, no clinics. Simply freeze the icepacks and ship it right out.

View Collection Instructions
4

Receive Your Personalized Protocol

Within 3-5 weeks, unlock your unique mitochondrial pattern and optimization strategy.

View Sample Report
Easy 5-minute buccal cheek swab you can do in the comfort of your home

What Your Analysis Reveals

Through advanced analysis of your electron transport chain activity, we uncover your unique cellular blueprint and exact optimization pathways.

  • Complete Mitochondrial Analysis

  • Science Behind Your Action Plan

  • Evidence-Based Recommendations

  • Specific Energy Production Bottlenecks

  • Personalized Food and Supplement Protocol

  • Clear Path to Peak Performance

How We Measure

Our breakthrough technology maps your unique mitochondrial pattern - something no blood test, genetic screen, or hormone panel can reveal.

Our comprehensive mitochondrial analysis measures five key cellular components that reveal how efficiently your cells produce energy:

01

Citrate Synthase Activity

We measure this critical enzyme from the citric acid cycle, which serves as a reliable indicator of your mitochondrial density. This tells us whether your body is producing enough mitochondria to meet your energy demands, or if it's working overtime to compensate for energy gaps.

02

Four Respiratory Chain Complexes

We analyze each of the four major energy-producing complexes (Complex I, II, II+III, and IV) individually.

This detailed breakdown allows us to:Identify which specific nutrients each complex needs for optimal performance

  • Determine if bottlenecks in particular complexes require adjustments to your protein, carbohydrate, or fat intake

  • Detect precise biochemical patterns that reveal exactly what's limiting your energy production

Advanced Mitochondrial Pattern Analysis

Our revolutionary process transforms complex cellular data into clear, actionable protocols.

How does the actual protocol optimize the mitochondria?
How Our Method Works (And Why It's Not Genetic Testing)

The Results?

Faster, more accurate insights that lead to immediate, personalized optimization strategies tailored to your unique mitochondrial profile.

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Featured Publications

Explore the research and insights advancing mitochondrial science and health.

Performance and Longevity

Optimize your cellular energy production for peak performance. Research shows mitochondrial nutrients significantly impact exercise performance and recovery, while mitochondrial decline (1% annually) directly influences aging.

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Ostojic SM. Mitochondria-targeted nutraceuticals in sports medicine: a new perspective. Res Sports Med [Internet]. Informa UK Limited; 2017 Jan [cited 2025 Jan 4];25(1):91–100. Available from: https://pubmed.ncbi.nlm.nih.gov/27855498/ PMID: 27855498

Guo Y, Guan T, Shafiq K, Yu Q, Jiao X, Na D, Li M, Zhang G, Kong J. Mitochondrial dysfunction in aging. Ageing Res Rev [Internet]. Elsevier BV; 2023 Jul [cited 2025 Jan 4];88(101955):101955. Available from: https://pubmed.ncbi.nlm.nih.gov/37196864/ PMID: 37196864

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Energy and Cellular Optimization

Breakthrough research has revealed mitochondrial dysfunction as a key factor in chronic fatigue and energy-related conditions. Our analysis targets these fundamental cellular mechanisms.

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Recent studies demonstrate that mitochondrial dysfunction plays a central role in chronic fatigue syndrome (ME/CFS), revealing the critical connection between cellular energy production and overall vitality. Our approach directly addresses these cellular mechanisms.

Booth NE, Myhill S, McLaren-Howard J. Mitochondrial dysfunction and the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Int J Clin Exp Med [Internet]. Int J Clin Exp Med; 2012 Jun 15 [cited 2025 Jan 4];5(3):208–220. Available from: https://pubmed.ncbi.nlm.nih.gov/22837795/ PMCID: PMC3403556

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Cognitive Function and Mental Health

Groundbreaking research reveals the critical role of mitochondrial health in cognitive function and mental well-being. Studies show Alzheimer's brains have ten times the mitochondrial DNA damage compared to healthy brains

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Studies have uncovered that mitochondrial function is fundamental to brain health, with dysfunction linked to various neurological and mental health conditions. Research demonstrates mitochondrial health's crucial role in autism spectrum disorders, schizophrenia, bipolar disorder, and depression.


  • Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances. Mol Neurodegener [Internet]. Springer Science and Business Media LLC; 2020 May 29 [cited 2025 Jan 4];15(1):30. Available from: https://pubmed.ncbi.nlm.nih.gov/32471464/ PMCID: PMC7257174
  • Kim Y, Vadodaria KC, Lenkei Z, Kato T, Gage FH, Marchetto MC, Santos R. Mitochondria, metabolism, and redox mechanisms in psychiatric disorders. Antioxid Redox Signal [Internet]. Antioxid Redox Signal; 2019 Aug 1 [cited 2025 Jan 4];31(4):275–317. Available from: https://pubmed.ncbi.nlm.nih.gov/30585734/ PMCID: PMC6602118
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Transformative Results

Learn how advanced mitochondrial analysis has helped others enhance their energy, performance, and longevity.

"I went into unexplained menopause at 28 years old for ten years, and nothing could restore my ability to menstruate without medication or hormone treatment. I tried everything, unsuccessfully—  conventional medicine, functional medicine, homeopathy, alternative therapies, diet and fitness changes, you name it.Just two weeks after trying one supplement Chris identified from my cheek swab as critical for my mitochondrial health, I began menstruating again. 100% true story."

"Very in-depth info on much of what is important for health… Here one gets insights that one cannot find in other places and that is approached from different angles."

"I have been struggling with severe episodes of reflux, extreme fatigue and stomach issues that have been getting worse and worse in the past few years. I was really starting to lose hope until I stumbled upon Dr Chris Masterjohn's work. I found out from the analysis that I had mitochondrial dysfunction affecting my cellular energy production, but it was something that could be fixed with targeted supplementation. The mitochondrial support I received has changed my life. I now can eat food and actually feel energized afterwards as my cells are properly converting nutrients into energy, it has made life so much more rewarding and fulfilling and I cannot thank Chris enough!"

"For a year after chemotherapy, I struggled with deep fatigue, brain fog, and scars that did not heal completely. This was the first time I found someone who looked at my issues as a mitochondrial dysfunction problem. Dr. Masterjohn suggested what I could do to test certain mitochondrial pathways that might be impaired based on the Mitome test results. These included diet changes to support cellular energy production, specific supplements targeting mitochondrial function, and therapy to boost mitochondrial activity. The resulting surge in cellular energy allowed me to start a strength training program, replacing muscle lost to muscle atrophy from chemotherapy. Scarring from treatment that was static for over a year completed healing and autoimmune issues settled down. This improvement in mitochondrial function was a significant turning point in my recovery and I'm looking forward to continued progress."

"The Mitome report’s supplement adjustments have been a game-changer. I used to struggle with frequent colds, a racing heart after caffeine or carbs, and low stress tolerance, which impacted my well-being and focus. Now, my energy is up, my blood sugar is steady, and I feel healthier and more productive overall. I’ve also fallen in love with music again, and my mood has greatly improved."

"I (34M) was a previously healthy 32 year old before I started having a myriad of health issues relating to stopping long term SSRI use. My symptoms were severe and included tachycardia, shortness of breath, neuropathy, sexual dysfunction, anxiety, muscle cramping, numbness, excessive urination. The constellation of symptoms brought me to see dozens of specialists who could not tell me what was going on. I am so grateful I came across Chris' work. Through the analysis, we discovered significant impairments in my mitochondrial electron transport chain, particularly in Complex II and III.

After reviewing my genetic data and mitochondrial function tests, we identified several key areas where my cellular energy production was compromised. Through targeted support of my mitochondrial pathways based on these findings, I quickly began to recover. This is after almost 2 years of being constantly sick. 6 months later, I have regained quality of life and am able to do everything I used to be able to. I am so thankful for Chris and his ability to discern how mitochondrial dysfunction can undermine many medical conditions. When I received the final report, he provided a clear protocol on how to improve my cellular energy production. I continue to improve weekly and am so excited for the future."

“It took about six months before I began to notice a major shift—but when it happened, it was profound. Almost overnight, I experienced a complete cessation of the negative emotional states I had lived with for so long—depression, anxiety, and mental fatigue simply stopped. Since that moment, any experience of mental or physical discomfort feels more like an observation than a struggle. This shift has made it much easier for me to relax and stay centered—something that used to be incredibly difficult. Recently, I decided to do a second round of mito.me testing, just over a year after starting the treatment, to see how far my mitochondrial function has come. I'm incredibly glad I repeated the test. I’m deeply grateful to Chris and the entire team who supported me through this journey. Their help has been instrumental in restoring my vitality—and for that, I truly thank them.”

“Great test. Results look great. Comprehensive suggestions to correct any issues are provided.”

Welcome to the Mitochondrial Revolution.

We’re done playing small. While others sell surface-level hacks, we go to the source—your mitochondria. Join the first real movement in health.