Advancing Mitochondrial Science
The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.
What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.
This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Featured Publications
Explore the research and insights advancing mitochondrial science and health.
Oxidative damage in glutaric aciduria type I patients and the protective effects of l-carnitine treatment: GUERREIRO et al.
Published ByWileyPublished DateDecember 1, 2018Protective effects of L-carnitine on behavioral alterations and neuroinflammation in striatum of glutaryl-COA dehydrogenase deficient mice.
Published ByElsevier BVPublished DateSeptember 30, 2021The pro-inflammatory cytokine tumor necrosis factor α stimulates expression of the carnitine transporter OCTN2 (novel organic cation transporter 2) and carnitine uptake via nuclear factor-κB in Madin-Darby bovine kidney cells.
Published ByAmerican Dairy Science AssociationPublished DateJune 1, 2015Nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials.
Published ByAmerican Society for Pharmacology & Experimental Therapeutics (ASPET)Published DateJuly 1, 2022Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs on mitochondrial energy metabolism.
Published ByElsevier BVPublished DateOctober 1, 2008Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain.
Published BySpringer Science and Business Media LLCPublished DateOctober 5, 2017Fumarate is a terminal electron acceptor in the mammalian electron transport chain.
Published ByAmerican Association for the Advancement of Science (AAAS)Published DateDecember 3, 2021Active site intermediates in the reduction of O(2) by cytochrome oxidase, and their derivatives.
Published ByElsevier BVPublished DateApril 1, 2012

Partner with Mitome™
Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.
Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.