Advancing Mitochondrial Science
The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.
What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.
This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Featured Publications
Explore the research and insights advancing mitochondrial science and health.
S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization
Published ByPortland Press Ltd.August 15, 1985August 15, 1985Intra-mitochondrial methylation deficiency due to mutations in SLC25A26
Published ByElsevier BVNovember 5, 2015November 5, 2015Biochemical issues in estimation of cytosolic free NAD/NADH ratio
Published ByPublic Library of Science (PLoS)May 3, 2012May 3, 2012SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondrial disorders
Published ByWileyMarch 1, 2017March 1, 2017A biallelic pathogenic variant in the OGDH gene results in a neurological disorder with features of a mitochondrial disease
Published ByWileyMarch 1, 2021March 1, 2021Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver
Published ByInt J Biol SciApril 12, 2021April 12, 2021Moving towards clinical trials for mitochondrial diseases
Published ByWileyJanuary 1, 2021January 1, 2021Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects
Published ByJ Nutr BiochemDecember 24, 2013December 24, 2013

Partner with Mitome™
Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.
Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.