Advancing Mitochondrial Science
The framework behind Mitome is built on a rigorous analysis of peer-reviewed scientific literature. While the specific interpretive model we use is proprietary and original, and also based on in-house analysis of the underlying test cross-referenced with comprehensive genomic and biochemical data, it is fundamentally grounded in decades of research on mitochondrial bioenergetics, nutrient biochemistry, and cellular metabolism.
What you’ll find below is not a list of studies conducted directly by our team, but rather the foundational research that informed the development of our methodology. We’ve taken what was once a test used almost exclusively for rare disease diagnosis and re-engineered its application to make it actionable for anyone seeking to optimize health, performance, and longevity at the cellular level.
This page is designed for transparency and scientific accountability—to show how we've built on the existing body of evidence to bring mitochondrial analysis into a new era of practical, personalized health optimization.

Featured Publications
Explore the research and insights advancing mitochondrial science and health.
Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria
Published ByElsevier BV;December 1, 2014December 1, 2014Discovery of a second citric acid cycle complex
Published ByElsevier BVMay 12, 2023May 12, 2023Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria
Published ByElsevier BVDecember 1, 2014December 1, 2014Methylene blue administration during and after life-threatening intoxication by hydrogen sulfide: Efficacy studies in adult sheep and mechanisms of action
Published ByOxford University Press (OUP)April 1, 2019April 1, 2019Antidotal effects of the phenothiazine chromophore methylene blue following cyanide intoxication
Published ByOxford University Press (OUP)July 1, 2017July 1, 2017Methylene blue induced O2 consumption is not dependent on mitochondrial oxidative phosphorylation: Implications for salvage pathways during acute mitochondrial poisoning
Published ByElsevier BVOctober 1, 2022October 1, 2022Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria
Published ByElsevier BVDecember 1, 2014December 1, 2014An evaluation of hydromethylthionine as a treatment option for Alzheimer’s disease
Published ByInforma UK LimitedApril 1, 2024April 1, 2024

Partner with Mitome™
Join the front lines of a revolution in health. We’re fighting back against decline, burnout, and biological guesswork — and we’re looking for partners who want to do the same.
Reach out to us at support@mito.me to explore affiliate and collaboration opportunities.