
Mitochondrial dysfunction has been found at the root of problems as diverse as chronic fatigue, Alzheimer’s, autism, schizophrenia, bipolar, depression, migraines, and a wide spectrum of neurological, muscular, gastrointestinal disorders, and aging. Mitochondrial function is even the limiting factor in exercise performance and recovery.
So what causes it?
We can obtain a critical clue by looking at the effect of aging itself.
Your cells are aging faster than you think. Studies show that mitochondrial function starts declining at roughly 1% per year by age 18, which means that by the age of 70, your capacity to produce energy could diminish by up to 52%.
This shocking statistic hits at a critical principle: we either grow or we die... and most of us spend most of our life slowly dying.
Consider how interconnected mitochondrial health is:
- Methylation is needed to produce ATP, but ATP is needed to activate the methylation system.
- ATP is needed to produce coenzyme Q10, and CoQ10 is needed to produce ATP.
- Methylation is independently needed to produce CoQ10, and since ATP is so important to methylation, CoQ10 is indirectly needed to support methylation.
In other words, everything you need to produce cellular energy is so interdependent that one small deficit in any one of them can turn a virtuous cycle supporting perpetual investment in long-term health into a vicious cycle of declining energy production.
Exposures to toxins, illnesses, and nutrient deficiencies can precipitate these deficits and can cause more of them to accumulate earlier in some people. But in every case, each of us are going to have our journey toward ascending or declining mitochondrial function shaped by our unique genetic idiosyncrasies.
Why Guessing Doesn’t Work
The first thing we should all be doing is eating a nutrient-dense diet that has no missing links limiting the ability of these nutrients to support our mitochondrial health.
But for many people, it’s not enough.
If your mitochondria are struggling due to idiosyncratic nutrient needs or blocks in fuel metabolism, no amount of general health advice will be precise enough. You’ll either waste years guessing—or worse, make things worse.
The big problem with guessing is that there are hundreds of different genes responsible for fueling the mitochondrial respiratory chain, where 90% of your cellular energy is made. One wrong guess and you can get yourself in trouble. For example, thiamin is necessary for mitochondrial function, and high-dose thiamin is a miracle for some people. But I have had one client who came to me after high-dose thiamin created a brand new form of motor dysfunction, and another whose practitioner swore by high-dose thiamin for dysautonomia but who had gotten five times worse and bedridden after adding it to her own routine.
When it comes to mitochondrial optimization, guessing can be dangerous.
Comprehensive genetic testing of every possible bottleneck is possible, but it’s prohibitively expensive and requires rare expertise to interpret.
Enter: Mitome
I (Chris) created Mitome to make mitochondrial optimization precise, accessible, and affordable.
Mitome measures all four respiratory chain complexes, tells you your "mitochondrial type," and gives you a precise cellular optimization protocol around it. It even curates a step-by-step order for the implementation of the protocol to leverage each synergy in the safest and most effective way possible. To use thiamin as in the previous example, I estimate about 7% of people will receive thiamin in their protocol, and it will generally be positioned as the 11th, 12th, or 15th step in the protocol depending on the exact nature of the bottleneck.
Precise knowledge is your single most important asset when trying to reverse chronic fatigue, psychiatric problems, or neurodegenerative disorders or transform cellular aging.
This is the kind of precision that makes the difference between frustration and breakthrough.
Mitochondrial function is the foundation of long-term health, mental clarity, energy, and longevity.
Order Mitome today and take the first step in unlocking your unique path to mitochondrial resilience.
Our mission is to be the driving force behind mitochondrial wellness, revolutionizing the way we understand and optimize human health from the cellular level. Through advanced pattern analysis, we uncover your specific cellular needs and create precise protocols to maximize your mitochondrial efficiency.
It's time to learn not just how well your mitochondria function, but why they could be run down and what is the best fuel to power them and the best therapy to heal them.
This Is Just the Beginning
At Mitome, we believe the future of health isn’t found in guesswork or generic plans. It lives inside your cells, in the mitochondria that power every heartbeat, every thought, and every transformation. You’ve just completed the first protocol ever designed to personalize your health strategy using real-time mitochondrial function. This isn’t a trend. It’s the beginning of a new era in biology.
We call it cellular warfare—because the enemies of your energy, performance, and longevity are real. And your protocol is your arsenal.